Use of clomiphene

For women. Clomiphene may be prescribed to:

-Stimulate ovulation in a woman who does not ovulate or who ovulates irregularly. Her estrogen levels and pituitary gland function must be normal, and her male partner must be diagnosed as fertile.

Perform a clomiphene challenge test, which is sometimes used to evaluate a woman's ovulation and egg quality (ovarian reserve). When given early in a woman's menstrual cycle for 5 days,
-clomiphene elevates a woman's follicle-stimulating hormone (FSH) level. On the next day, an FSH blood level that has dropped back to normal is a sign of a normal ovarian reserve and ovulation. An elevated FSH is a sign of low ovarian reserve. Women with a diminished ovarian reserve can use donor eggs, which greatly improves their chances of giving birth to a healthy child.

- Stimulate the development of multiple eggs for use with assisted reproductive technology, such as in vitro fertilization (IVF) or gamete intrafallopian transfer (GIFT).

- Regulate ovulation in a woman who ovulates irregularly and/or is going to have intrauterine insemination or artificial insemination.