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Xylocaine: Where not to use with Adrenaline?

"Digital PEN"
* Digits (Fingers and toes)
* Penis
* Ear
* Nose tip
Adrenaline causes vasoconstriction
which helps to trap Xylocaine
(anaesthetic) locally prolonging its
duration of action. The two are not
used together at sites supplied by end arteries as the vasoconstriction
produced by adrenaline can cause
ischemic necrosis of the tissues

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