MEDICAL SEARCH ENGINE

SEARCH RESULTS

cystic fibrosis


Def/intro#most commen life limiting
autosomal recessive genetic disorder
MOLECULAR GENETICS
mutation in(CFTR) cystic fibrosis
tranmembrane conductance regulator gene which regulate
chloride conductance channel
CLINICAL FEATURES
1]Recurrent lower respiratory tract infection
2].Bronchiectasis
3].Malabsorption
4].Steatorrhoea
5].Azoospermia 6].Pancreatic insufficiency
DIGNOSIS
high sweat chloride>60mEq/Ltest
MANAGEMENT
A].RESPIRATORY MANAGEMENT
1.Airway Clearance Technique
postural drainage&cyclical breathing,positive expiratory pressure
2.Mucolytic agent
¤N-acetyl cystein breaks sulphydryl bond of mucous
¤.Recombinant human DNAase
3.Antibiotics theraphy
like ceftazidime,cefoperayone with aminoglycosides are given
4.Bronchodialators& inhalation therapy
B]NUTRITIONAL MANAGEMENT
1.Increasing caloric intake
2.Supplementation of fat soluble
vitamins
3.Sodium supplement
4.Pancreatic enzyme supplement.
ation with enteric coated spherules
dose=initial.3000(1/3capsule)to
10,000IU(one capsule)per meal

No comments:

Post a Comment

LinkWithin

Related Posts Plugin for WordPress, Blogger...